Interní Med. 2007; 9(1): 32-35

The treatment of secondary hyperparathyroidism in practice

MUDr. František Švára

Interní oddělení Strahov, Všeobecná fakultní nemocnice, Praha

The current opinion o the disorder of calcium metabolism and phosphorus in chronic renal failure is much wider than in the past. The disorder is considered to be multisystemic disease, which most important components besides bone changes itself are associated biochemical deviations in laboratory markers of bone metabolism and presence of vascular and other nonskeletal calcifications. The complex view on the problem resulted in a new term – Bone and mineral disorder in chronic renal disease. Based on results of large mortality studies current treatment does not focus on suppression of hyperparathyroidism. Our goal is to reach and maintain in the long-term optimal values of bone metabolism parameters in the area of mineral balance, mainly values of calcium and phosphates. The ultimate goal is decrease of prevalence (or at least a delay) of vascular calcifications and decrease of cardiovascular morbidity and mortality.

Keywords: Key words: secondary hyperparathyroidism, phosphate binders, vitamin D analogues, calcium mimetics.

Published: January 1, 2007  Show citation