Interní Med. 2011; 13(1): 38-42

Phytoestrogens and their application in menopause

prof.Dr.RNDr.Oldřich Lapčík, PharmDr.Lucie Sosvorová
Ústav chemie přírodních látek, Fakulta potravinářské a biochemické technologie,

Phytoestrogens are a structurally heterogenous group of plant polyphenols that are able to activate vertebrates estrogen receptors.

Their main representatives in human diet are isoflavones and lignans. For more than twenty years, phytoestrogens are considered to

alleviate menopausal symptoms. Pre-clinical trials have demonstrated their potential to act positively on bone metabolism, cardiovascular

system, menopausal vasomotor symptoms and to decrease the risk of breast cancer. The evidence of clinically relevant effects of

phytoestrogens is still rather limited. The menopausal women‘s choice of phytoestrogen food supplements is more often influenced by

advertisement than by a physician´s reccomendation.

Keywords: phytoestrogen, isoflavone, menopause, HRT

Published: January 14, 2011  Show citation

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Lapčík O, Sosvorová L. Phytoestrogens and their application in menopause. Interní Med. 2011;13(1):38-42.
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