Interní Med. 2014; 16(4): 152-155
Upper gastrointestinal bleeding is the most common acute event in gastroenterology. Despite an increase in the treatment options, the
overall mortality rate has virtually remained unchanged in the recent decades, particularly due to a higher incidence and mortality rate
of bleeding in elderly people. It is imperative to initiate pharmacotherapy prior to endoscopy. In non-varicose bleeding, proton pump
inhibitors are indicated, in varicose bleeding vasoactive agents and antibiotics. Early endoscopy can be used to achieve hemostasis in
over three-quarters of individuals, regardless of the type of bleeding. Pharmacotherapy must be continued even after the bleeding has
been stopped, with subsequent prophylaxis of recurrence in those indicated for it (H. pylori eradication, proton pump inhibitors, beta
blockers, variceal eradication).
Published: June 1, 2014 Show citation