Internal Medicine for Practice, 2006, issue 6

Editorial

Slunce budiž pochváleno?

Mgr. Iva Daňková

Interní Med. 2006; 8(6)

Review articles

Pulmonary arterial hypertension in congenital heart disease

MUDr. Pavel Jansa

Interní Med. 2006; 8(6): 266-269

Pulmonary arterial hypertension (PAH) is a heterogeneous group of diseases that share the prekapilary pulmonary hypertension, similar pathophysiology (with vasoconstriction, remodeling of pulmonary arteries and thrombosis) and options of specific pharmacotherapy. In the group of PAH, especially PAH in systemic connective tissue diseases, congenital left-to right shunts, portal hypertension, HIV infection and abuse of certain anorectics are together with idiopathic and familial PAH included. Pulmonary hypertension is present in about 10% of patients with congenital heart disease in adults. Most frequently it is a consequence of recirculation across...

Instruction for prevention of bacterial endocarditis

doc. MUDr. Petr Heinc Ph.D

Interní Med. 2006; 8(6): 270-273

Bacterial endocarditis unexpectedly develops in a case of bacteremia resulting from mucosal or skin surface damage but mostly it occurs due to injury during planned medical instrumentation. Year incidence of bacterial endocarditis is only 2–5/100 000 inhabitants but it’s mortality is about 10–30%. Risk of bacterial endocarditis increases with severity of the underlying heart disease and therefore the prophylaxis of bacterial endocarditis seems to be unavoidable. Patients with heart diseases are divided into groups associated with high, mild and negligible risk of bacterial endocarditis, with a special regard to mitral valve prolapse...

Chronic obstructive lung disease-the importance of early diagnosis and treatment

MUDr. Vladimír Zindr

Interní Med. 2006; 8(6): 274-279

Chronic obstructive lung disease is a serious problem because of its prevalence, mortality and economical burden of the society. The most effective intervention is limitation of risk factor exposure. An early diagnosis is essential followed by smoking cessation. Bronchodilatation therapy brings a long-term relieve of symptoms, improved quality of life and reduction in number of exacerbations. Pulmonary rehabilitation improves the degree of dyspnoea, exercise tolerance, general health state and decreases the need of health care. An early diagnosis is a basis for optimal treatment results.

Tick born diseases

MUDr. Hana Roháčová Ph.D

Interní Med. 2006; 8(6): 280-283

The article sumarises tick borne transmited diseases. Attention is given to the diseases presented in the Czech republic-tick borne encephalitis, Lyme borreliosis, ehrlichiosis, tularemia. Characterization of the vector, its life cyklus, possibilities of defence are described in the introduction. The attention is paid not only to the clinical picture, but especially to diagnostic, strategy of dispenzarization, therapy and prophylaxis.

Case report

Osteoporóza jako dominantní projev nesekretorické formy mnohočetného myelomu

MUDr. Tomáš Pika, MUDr. Markéta Zemanová Ph.D, prof. MUDr. Vlastimil Ščudla CSc, MUDr. Vlastislava Tichá CSc

Interní Med. 2006; 8(6): 296-298

Možnosti léčení chronické žilní insuficience s využitím gelů s vyšší koncentrací heparinu

MUDr. Jan Marušiak Ph.D

Interní Med. 2006; 8(6): 299-300

Interdisciplinary overviews

Paget‘s disease - advances in treatment

MUDr. Jiří Jenšovský

Interní Med. 2006; 8(6): 284-287

Paget‘s disease is the second most common metabolic disorder of the skeleton. It is a chronic condition which requires long-term, if not lifetime, treatment. Due to a primary disorder at the level of osteoclast clones, the treatment involves drugs inhibiting their action or reducing their number. Historically, the first agent to have been used was synthetic salmon calcitonin. Until recently, the treatment of Paget‘s disease included either oral bisphosphonates given in multiples of the daily doses used in osteoporosis treatment or intravenous bisphosphonates administered repeatedly at several month intervals. In the autumn of 2005, the...

Depression common with somatics disorders - tianeptin in primary care

prof. MUDr. Jaroslav Bouček CSc

Interní Med. 2006; 8(6): 288-291

Depression (D) is serious, chronic disease of the brain, affecting 10% of the population. At the same time full life prevalence is 17%. D is the disorder, which is combined with the lowest level of social position and physical performance as compared to diabetes, hypertension or arthritis. D requires continuous and supportive treatment, however it is often insufficiently diagnosed and treated. There is a big mortality combined with depression, additionally cognitive functions are affected as well as endocrine changes are present and immunological response is decreased. D occurs with big range of different somatic diseases, and diagnosing it improves...

Diagnostics and therapy of chronic rhinosinusitis

MUDr. Jan Rottenberg

Interní Med. 2006; 8(6): 292-295

Chronic sinusitis – with its 15% prevalence in population – represents one of the most common diseases in everyday practice in otolaryngology. The aetiology of chronic sinusitis is endogenous: the most frequent cause of the disease is allergic and non-allergic hypersensitivity of the immune system. The diagnostics covers a wide range of nosologic units including diseases with serious prognosis, which, if misdiagnosed – may lead to death or serious health damage. The therapy of chronic sinusitis must reflect the aetiology of the disease – the most frequent method of treatment is functional endoscopic sinus surgery in combination...