Internal Medicine for Practice, 2005, issue 9

Editorial

Zlínský kongres vyzývá k interdisciplinární spolupráci

prof. MUDr. Jaroslav Rybka DrSc

Interní Med. 2005; 7(9): 379

Review articles

News in the treatment of diabetic nephropaty

doc. MUDr. Vladimír Tesař DrSc

Interní Med. 2005; 7(9): 384-386

Diabetic nephropathy is the most frequent cause of end-stage renal failure in developed countries and its prevalence is steadily increasing. Patients with diabetic nephropathy are, however, endangered more by their high cardiovascular mortality than by the development of end-stage renal failure. Treatment of hypertension with the target blood pressure lower than 130/85 mm Hg lowers in patients with diabetic nephropathy not only cardiovascular risk, but also the risk of progression of the renal disease. While the renoprotective effect of the angiotensin converting enzyme inhibitors and angiotensin antagonists is well documented, evidence for their...

Clinical and diagnostic problems of abdominal aortic aneuryzm

MUDr. Dáša Kmecová, MUDr. Július Kmec CSc, MUDr. Eva Szabóová PhD

Interní Med. 2005; 7(9): 388-391

The diagnosis of aneurysms of the abdominal aorta (AAA) belongs to frequent medicinal problems. In the majority of cases the natural history of the AAA is asymptomatic and the rupture is quite often the first symptom. The prognosis of patients with ruptured AAA is extraordinarily unfavourable in comparison with electively operated patients. That is why looking for patients with AAA, their dispensarization in the case of small size aneuryzms, elective surgical or endovascular treatment in the case of sizes bigger than 5cm and an urgent diagnosis and treatment of the ruptured AAA are necessary. This can save many lives in the elderly population. The...

Bronchogenic carcinoma: new trends in diagnosis and therapy

prof. MUDr. Miloš Pešek CSc

Interní Med. 2005; 7(9): 392-394

The author presents basic epidemiologic data concerning lung cancer, its symptoms and population at risk. The essential of diagnosis in the suspected cases are a history, physical exam, chest X-ray in 2 projections, bronchoscopy and computed tomography of the chest. In the article we can find technical and staff requirements for equipment of a centre for diagnosis and treatment of bronchogenic carcinoma. The author emphasizes especially interdisciplinary approach. Internists and cardiologists play an important role in preoperative preparation of patients, general practitioners in diagnosis and therapy.The author suggests an algorithm of therapeutic...

Hypertriglyceridemia (pathogenesis, diagnosis, therapy)

MUDr. Jan Buryška

Interní Med. 2005; 7(9): 395-398

While in previous years, priority in the field of lipidology was devoted to total cholesterol(TCH), and LDL cholesterol (LDLch), nowadays this priority shifts towards populations with moderately increased concentration of LDLch and with dyslipidemia typical for 2nd-type diabetes mellitus (DM2T) and towards metabolic syndrome (MS). Dyslipidemias are characterized by mildly increased concentration of triglycerides (Tg), decreased concentration of HDL cholesterol (HDLch) and by the boost of small-density LDL particles. Besides these highly aterogenic dyslipidemias, there exist hypertriglyceridemias (HTG) with a low risk of cardiovascular disease (CVD)....

Case report

Akutní infarkt myokardu

MUDr. Jana Bednářová, MUDr. Pavel Červinka Ph.D., FESC, FACC, MUDr. Josef Dražka, MUDr. Milena Kubíčková

Interní Med. 2005; 7(9): 408-409

Thymom v klinické praxi

Ladislav Slováček, prof. MUDr. Ladislav Jebavý CSc, prof. MUDr. Jaroslav Kačerovský CSc

Interní Med. 2005; 7(9): 410-411

Interdisciplinary overviews

Modern pharmacotherapy for insomnia

prof. MUDr. Karel Šonka DrSc, prof. MUDr. Soňa Nevšímalová DrSc

Interní Med. 2005; 7(9): 401-404

Insomnia is a most frequent disease. Chronic insomnia is carefully studied in terms of etiology, and, in terms of therapy, classified as secondary if it is concomitant to some other disease, in which case treatment is directed toward the latter, and as primary insomnia. Pharmacotherapy for insomnia is represented mainly by hypnotics (benzodiazepines and hypnotics of the 3rd generation), and by some sedatively acting antidepressants. An overview is presented of some currently applied medicinal products designed to control the condition.

ANTIDEPRESSANTS IN THE TREATMENT OF MALE SEXUAL DYSFUNCTION

prof. MUDr. Alexandra Žourková CSc

Interní Med. 2005; 7(9): 405-407

The author describes studies of therapeutic efficaccy of antidepressants in the treatment of male sexual dysfunction. Antidepressants stimulating sexual activity (moclobemide, bupropion, trazodone) demonstrate good results in the therapy of decreased libido and erectile dysfunction, serotonergic antidepressants are used in the treatment of premature ejaculation.