Děloha na leasing

MUDr. Radkin Honzák, CSc.

Interní Med. 2010; 12(3): 123  

Pharmacological management of chronic heart failure

doc.MUDr.Radek Pudil, Ph.D.

Interní Med. 2010; 12(3): 126-130  

In the last years, the number of patients with chronic heart failure is increasing. Heart failure is a frequent cause of hospitalizations. Despite the progress in therapy, heart failure has high rate of hospitalization admissions and mortality. Pharmacological management can significantly improve the course of the disease. The article is a review of pharmacotherapy of chronic heart failure, it discuss indications of the drugs and pitfalls of the therapy. Therapy of chronic heart failure is rather complex, it requires identification of the cause and precipitating factors, which can make it worsen.

Allergic rhinitis, diagnosis and therapy

MUDr.Zuzana Humlová

Interní Med. 2010; 12(3): 131-135  

Allergic rhinitis is the most common diagnose among atopic diseases in the population. Its previous classification on to seasonal allergic rhinitis and perennial allergic rhinitis has been abandoned. Contemporary classification is based on intensity of symptoms, their duration and an impact of quality of life. The most important allergens are pollen grains, moulds, mites, animal danders, occupational allergens, food and drugs. Etiopathogenesis of allergic rhinitis is based on IgE – mediated response of organism onto frequent contact with an allergen. Eosinophilic inflammation is then the final result of this activation. Suppression of...

Management of resistant hypertension

MUDr.Filip Málek, Ph.D., MBA

Interní Med. 2010; 12(3): 136-139  

Despite the progress of the therapy and target organ damage diagnostics in the patiens with arterial hypertension, issue of resistant hypertension is still actual. The prevalence of resistant hypertension, which is defined as the inability to reach target blood pressure values with three antihypertensiv drugs diuretics included, is about 30 % in hypertensive subjects. After exclusion of the secondary hypertension, when the most common cause are: primary hyperaldosteronism, chronic kidney disease and renovascular hypertension, the main cause of the resistant hypertension are: white coat phenomenon, poor life-style control, low adherence of the...

Possibilities of affecting the immune system with nutraceutics

doc.MUDr.Pavel Kohout, Ph.D.

Interní Med. 2010; 12(3): 140-144  

Nutraceutics are functional foods or food supplements that are close to medications in their action on the human organism although, more often than not, effectiveness in preventing diseases is confirmed. Nutraceutics differ in their chemical composition and affect various organs of the human body. The effects of some groups of nutraceutics on the immune system have been confirmed in clinical trials, e.g. those of probiotics, prebiotics, and essential fatty acids.

Familial adenomatous polyposis - recommendations for screening and follow-up

MUDr.Jan Trna, MUDr.Oldřich Stibůrek, MUDr.Kateřina Klímová, MUDr.Martina Mišejková, MUDr.Jan Šlapák, MUDr.Oldřich Robek

Interní Med. 2010; 12(3): 145-147  

Familial adenomatous polyposis primarily endangers its carriers with development of colonic cancer. However, the extracolonic involvement associated with this disease can also have serious consequences for patients. Recognition of a causal connection of extracolonic findings with the basic diagnosis of familial adenomatous polyposis can lead to early diagnosis and well-timed surgical treatment of asymptomatic patients without a family history of familial adenomatous polyposis and/or colorectal cancer. The article further proposes a system of patients follow-ups after successful surgical treatment.

Obstructive sleep apnea syndrome

MUDr.Milada Hobzová

Interní Med. 2010; 12(3): 148-151  

The sleep apnea syndrome is a disease connected with sleep but its consequences remain even in lucidity. A typical daily sign is the excessive somnolence, especially during monotonous activities and microsleeps. At night the symptoms are snoring and apneas during sleep. The consequences of untreated sleep apnea syndrome are not only medical (significant impact on cardiovascular system) but also socio-economic – microsleeps may cause traffic accidents in drivers. Therefore a targeted investigation for this disease must be applied.

Infected posttraumatic false aneurysm and gangrene of the shin

MUDr.Jana Pometlová, MUDr.Milan Šír, doc.MUDr.Leopold Pleva, CSc.

Interní Med. 2010; 12(3): 159-162  

Posttraumatic false aneurysm is rare cause of lower etremity soft tissue ischaemia and consequently gangrene. Posttraumatic false aneurysm with surrounding soft tissue compression is not the common cause of lower extremities gangrene development. It almost always leads to poorly managed bleeding from the injured artery while gangrene curing. Ischaemia of surrouding soft tissue almost always lead to the development of the treatment resistant infection, which in some cases should be solved by amputation of the affected limb. In order to manage those stares it is needed to use all the available treatment methods to be able to decrease consecutive...

Primary headache

MUDr.Jiří Mastík

Interní Med. 2010; 12(3): 152-154  

International Classification of Headache Disorders recognizes primary and secondary type of headache. Primary headache has no underlying organic or structural laesion and all the clinical investigations are normal. There are three main types of primary headache – migraine, cluster headache and other trigeminal autonomic cephalalgias and tension-type headache and each has its specific treatment. Secondary headache has its uderlying condition, either organic or structural intra-/extra-cerebral laesions or dysbalance of homeostasis or administration/whithdrawal of various chemical agents. It is essential to differentiate between primary...

Subends’ problems

MUDr.Milena Jirásková, CSc., Ing.Lubor Jirásek, CSc.

Interní Med. 2010; 12(3): 155-158  

Article informs readers on the current ongoing current issues relating to the risks of solar and artificial UV radiation in sun parlors.

Differential diagnosis and treatment of lower limb oedema

MUDr.Sylva Zajícová

Interní Med. 2010; 12(3): 167-170  

Lower limb oedema is a common reason for seeing a physician. The paper summarizes the aetiology, clinical presentation, differential diagnosis and treatment of individual types of oedema with a focus on lower limb oedema, chronic venous insufficiency and lymphoedema. Correct diagnosis of oedema is essential for choosing adequate therapy.

Osteoporosis prevention

MUDr.Jiří Jenšovský

Interní Med. 2010; 12(3): 163-166  

Osteoporosis is a disease with a significant genetic component and a number of possible risk situations due to its origin and development throughout life. Therefore, osteoporosis prevention must begin as early as childhood, continue in adulthood – when the maximum possible peak bone mass needs to be achieved – and last for the rest of a person‘s life. Adequate calcium and vitamin D intake and enough exercise are always essential. Risk factors including associated diseases and risk medications need to be monitored. Surveillance of individuals at risk and screening and monitoring by use of DXA measurement are required and fractures...

Autodidaktický test 3/2010

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Interní Med. 2010; 12(3): 171