Internal Medicine for Practice, 2005, issue 4

Editorial

Pomáhejme jaru na svět, jinak za rok nemusí přijít

PhDr. Dušan Třeštík

Interní Med. 2005; 7(4): 163

Review articles

Facilitated primary percutaneous coronary intervention - the current view

MUDr. Pavel Boček

Interní Med. 2005; 7(4): 167-169

The treatment of acute ST segment elevation myocardial infarction (STEMI) passed through important development concentrated on prognostic impact of the patients during last 20 years. Primary percutaneous coronary intervention (pPCI) became the method of the choice in this situation. Nowadays the possibility how to combine the advantage of immediately accessible fibrinolytic therapy and PCI provided immediately after transportation of the patient to the PCI centre is searched for. This approach is named facilitated PCI. The principal idea is that as earlier the flow in the infarct related artery is restored, as better prognosis of the patients. As well...

RISK REDUCTION AND STRATEGIES TO PREVENT GI COMPLICATIONS OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS

MUDr. Bohumil Seifert

Interní Med. 2005; 7(4): 170-173

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly used drug class in the world. Low-dose aspirin (ASA) is widely used for cardiovascular and cerebrovascular prevention. Their use is limited by GI side effects. These side effects include dyspepsia, gastroduodenal ulcers and complications, such as bleeding or perforation, in 1–4% of patients per year. The side effects occur also in lower part of GI tract behind duodenum. The risk of GI complication associated with NSAID therapy or ASA prevention is not the same for all patients. Factors associated with an increased risk include a past history of ulcer disease and complications,...

Bisoprolol in therapy of chronic heart failure

doc. MUDr. Helena Němcová CSc

Interní Med. 2005; 7(4): 174-176

Chronic heart failure is a disorder of heart as a pump. It is accompanied by a number of symptoms resulting from impaired contractility and decreased cardiac output. A number of neurohumoral systems is activated and becomes a target of the treatment. Bisoprolol is a highly selective β1-blocker. Its use in patients with chronic heart failure improves the function of the left ventricle, decreases the heart rate and may influence also a remodelation of the left ventricle. In large randomized trials in patients with chronic heart failure it was shown that therapy with bisoprolol increases the life expectancy, decreases the sudden death rate, total...

ConteMporary clinical recommandetion for therapy of asthma

MUDr. Viktor Kašák

Interní Med. 2005; 7(4): 178-181

Contemporary therapy of asthma the view recently revised publication Global strategy for asthma management and prevention by Global Initiative for Astma (GINA), is presented in this article.

Oral anticoagulant therapy

MUDr. Petr Kessler

Interní Med. 2005; 7(4): 182-185

Warfarin is widely used in prophylaxis and treatment of thrombosis. Mechanism of it’s action is very complex, the dose – response relationship is hard to predict. The risk of bleeding associated with its use is substantial. This risk may be decreased by careful monitoring, optimalization of INR target range and by avoidance of significant drug interactions. Optimal duration of treatment in an individual patient with venous thromboembolism may be prescribed by using recurrence risk assessment.

Case report

Jícnová stimulace síní - jednoduchá metoda v diagnostice palpitací

MUDr. Kamil Tachir

Interní Med. 2005; 7(4): 194-196

Akutní infarkt myokardu u dvou mladých pacientů

MUDr. Ondřej Toman, MUDr. Martin Poloczek, MUDr. Mgr. Jiří Pařenica, MUDr. Milan Kozák Ph.D, MUDr. Petr Kala Ph.D, prof. MUDr. Jindřich Špinar CSc

Interní Med. 2005; 7(4): 198-200

Interdisciplinary overviews

Urinary incontinence from a neurologist‘s perspective

MUDr. Jan Mareš, doc. MUDr. Roman Herzig Ph.D, prof. MUDr. Petr Kaňovský CSc

Interní Med. 2005; 7(4): 187-192

Urinary incontinence (UI) may occur in a series congenital and acquired disorders. It can rise by the system disorders of the emiction reflex. In this paper is described the recent view on the classification, the diagnostic and the treatment of UI especially in view of the neurogenic causes.