Internal Medicine for Practice, 2006, issue 9

Editorial

Lékař jako normalizátor

prof. MUDr. Stanislav Komenda DrSc

Interní Med. 2006; 8(9): 371

Review articles

Thrombophilic disorders

MUDr. Petr Kessler

Interní Med. 2006; 8(9): 374-379

Thrombophilic disorders are defined as inherited or acquired defects, pathophysiologically and statistically associated with an increased risk of thrombosis. Venous thromboembolism (VTE) is the most prominent manifestation of thrombophilia. Inherited abnormalities include deficiencies of antithrombin, protein C, and protein S, factor V Leiden mutation, and the prothrombin G20210A mutation. Acquired APC resistance, hyperhomocysteinemia, sticky platelet syndrome and elevated levels of factors VIII, IX and XI also have been associated with an increased risk of VTE. Acquired thrombophilic disorders are represented by antiphospholipid syndrome and cancer....

Acute states in phlebology

MUDr. Markéta Kaletová, MUDr. Dalibor Musil Ph.D

Interní Med. 2006; 8(9): 380-384

Deep vein thrombosis, superficial vein thrombosis and acute leg varices bleeding bring patients a major complications. We summarize information about diagnostic, treatment and prevention those diseases, mainly information about recurrence of deep vein thrombosis, the bleeding risks of anticoagulacion and deciding about duration of anticoagulant therapy. We emphasize the duplex ultrasonography as a fast and easy diagnostic method of venous diseases and importance of this method for early disclosure of superficial vein thrombosis extension to deep vein system. We assume the most importance for acute leg varices bleeding is prevention with surgical removing...

Hypokalemia

doc. MUDr. Romana Ryšavá CSc

Interní Med. 2006; 8(9): 385-388

Hypokalemia is one of the most frequent ion disorders in internal medicine and if recognised late it might have lethal consequences because of malignant arrhythmia. There is a number of congenital disorders leading to hypokalemia (endocrine disease-primary hyperaldosteronism, Cushing’s syndrome/disease, renal tubular disorders-Bartter’s, Giteman’s, Gordon’s syndrome etc.) that constitute of only about 1% of all cases of hypokalemia. In most cases it is an acquired state that is frequently iatrogenic, caused by therapy (diuretics). As hypokalemia we consider levels of potassium below 3,5 mmol/l; life threatening are levels below...

PREVENTION AND TREATMENT OF GLUCOCORTICOID-INDUCED OSTEOPOROSIS

MUDr. Michal Scheinost, prof. MUDr. Karel Pavelka DrSc, MUDr. Simona Skácelová, MUDr. Gabriela Šimková, MUDr. Radka Svobodová

Interní Med. 2006; 8(9): 389-392

Glucocorticosteroid-induced osteoporosis (GIOP) is a chronic disabling disease with high mortality, common social isolation of the patients, and last, but not least, astronomical economic consequences. GIOP is the most frequent of all secondary types of osteoporosis owing to their widespread use. The safe dose of glucocorticoid does not exist, that is why every administration of prednison or its equivalent in a dose of 5 mg and more for a period of 3 months should be complemented with preventive calcium and vitamin D suplementation. The prevention of GIOP is essential but the prescribing of preventive medication for corticosteroid induced loss...

Some notes about treatment of dyslipidemia

MUDr. Michal Vrablík Ph.D

Interní Med. 2006; 8(9): 393-395

Treatment of dyslipidemia has become a corner stone of intervention of the patients with increased cardiovascular risk. There are complex recommendations for dietary and physical activity changes without which the therapeutic success cannot be achieved. We have several types of hypolipidemic drugs (statins, fibrates, resins, ezetimibe, niacin). Other compounds can also be used in modification of plasma lipid levels (antiobezitics, some antidiabetics, estrogens). When side effects of the treatment occur it is necessary to test the tolerance of another drug of the same class or achieve better control of the metabolic disorder with a combination of hypolipidemic...

Blood pressure measurement

doc. MUDr. Helena Němcová CSc

Interní Med. 2006; 8(9): 396-400

The blood pressure measurement is one of the most frequently performed procedures in a physician office. It is described as a “causal blood pressure”. The severity of hypertension is better reflected by home blood pressure measurement. 24 hour blood pressure monitoring provides even more precise information about a blood pressure profile. Standard measurement of blood pressure by indirect auscultation method uses a mercury sphygmomanometer on arm. Systolic blood pressure is read in the 1st phase and diastolic in the 5th Korotkoff phase. In specific situations accompanied by increased cardiac output, the diastolic blood pressure is read...

Information

Jak se píše článek do prestižního mezinárodního časopisu?

Radka Klimešová, doc. MUDr. Petr Petr PhD, Alexandr Popkov

Interní Med. 2006; 8(9): 410-411

Doplněk stravy zaregistrován mezi léky

Ing. Ivan Mach, doc. MUDr. Daniel Pella Ph.D., FICC

Interní Med. 2006; 8(9): 412-414

Case report

Nález Mycobacterium celatum u pacienta s karcinomem hrtanu a plicní tuberkulózou v anamnéze

MUDr. Dana Štembírková, MUDr. Pavel Vodvářka Ph.D, MUDr. Dagmar Molendová, MUDr. Zbyněk Vrba, MUDr. Radek Nosál, MUDr. Štefan Litomerický, MUDr. Ludmila Neumann, Dr. Udo Reischl, MUDr. Jarmila Kaustová