Jenom slova?

MUDr. PhDr. Petr Pastucha

Interní Med. 2007; 9(12): 539  

Irritable bowel syndrom

prof. MUDr. Milan Lukáš CSc

Interní Med. 2007; 9(12): 544-547  

The funtional bowel disorders and especialy irritable bowel syndrome and functional large bowel dyspepsia are the final diagnosis in many of our patients. The irritable bowel syndrome is characterised by changes of bowel habits with abdominal dyscomfort or abdominal pain. The pathophysiology of irritable bowel syndrome is still not completely understood, but many factors are considered: a) abnormal motility pattern includes of the pathologic gastro-colic reflex; b) postinfective consequences in the large bowel mucosa; c) visceral hyperalgesia and increased perception of physiological or minor noxious stimuli; d) abnormal intestinal secretion with accumulation...

Therapy of venous thrombosis

MUDr. Alena Broulíková CSc

Interní Med. 2007; 9(12): 548-551  

The most common treatment of venous thrombosis are drugs with anticoagulant effect. Only a part of patients is treated with thrombolytic therapy and only small part is available for the surgical treatment. The heparin is the first treatment for the anticoagulant therapy. The choice is intravenous infusion with unfractionated heparin or low-molecular-weight heparin (LMWH) subcutaneously. Immediately with heparin you need to give anticoagulation therapy with warfarin. The advantage of LMWH is that therapy is not necessary to be controled by laboratory testing and the therapy is for patients more suitable and finally the patient can be controled in out-patients...

Hypertriglyceridemic waist and cardiovascular risk

MUDr. Michal Vrablík Ph.D

Interní Med. 2007; 9(12): 552-554  

Cardiovascular diseases have multifactorial etiology. There is no single dominant risk factor that is responsible for most of its prevalence. That is the reason why combined markers are being searched for, which would enable a more precise estimation of risk of atherosclerosis and its complications. One of them is so called hypertriglyceridemic waist. It is a current phenotype characterized by increased waist circumference and fasting triglycerides over 2 mmol/l. Hypertriglyceridemic waist is a marker of metabolic lipid and sugar disturbances and reflects very well pathological changes of postprandial metabolism. In clinical studies hypertriglyceridemic...

Progression of chronic kidney disease

doc. MUDr. Vladimír Tesař DrSc

Interní Med. 2007; 9(12): 555-557  

Chronic kidney disease frequently progresses to end-stage renal failure even after the stabilization of the underlying renal disease. Mechanism of the progression still remains not completely elucidated. Except from glomerular hypertension both tubular and interstitial damage due to proteinuria and direct damage to the podocytes were suggested as potential culprits. Progression of chronic renal failure can be slowed down by the optimal control of the blood pressure and by the administration of angiotensin enzyme inhibitors and angiotensin antagonists. Experimental studies suggest that even regression of glomerulosclerosis and improvement of the renal...

Atrial fibrillation management - therapeutic concept in the light of evidence-based medicine

MUDr. Jan Galuszka Ph.D

Interní Med. 2007; 9(12): 558-563  

Atrial fibrillation (AF) is the most common clinically important cardiac arrhythmia with increasing prevelance with age. That is why AF is compared to epidemy of moderm age and why AF encourages increasing attention during last decades. Expansion of knowledge targeting etiopathogenesis of AF and therapeutical priorities together with advances in catheter–based ablation technologies extorted need of revision of practice guidelines from 2001. New ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation were published in 2006. Therapeutic strategy in patients with AF involves prevention of thromboembolism, rate control of arrhythmia...

Kdo káže vodu a pije víno

prof. MUDr. Jindřich Špinar CSc, MUDr. Ondřej Ludka Ph.D, MUDr. Viktor Musil

Interní Med. 2007; 9(12): 577  

II. interní klinika LF MU a FN u sv. Anny v Brně oslavila šedesátku

doc. MUDr. Miroslav Souček CSc, MUDr. Petr Svačina

Interní Med. 2007; 9(12): 578  

Kontrola hlavních rizikových faktorů provázejících hypertenzi

prof. MUDr. Jiří Widimský DrSc., FESC, doc. MUDr. Miroslav Souček CSc, MUDr. Martina Sachová

Interní Med. 2007; 9(12): 571-574  

Absces štítné žlázy jako komplikace biopsie tenkou jehlou

MUDr. Milan Halenka, MUDr. Irena Škodová, MUDr. David Horák Ph.D, MUDr. Ladislava Kučerová, doc. MUDr. Petr Hejnar Ph.D, MUDr. David Karásek Ph.D, doc. MUDr. Zdeněk Fryšák CSc

Interní Med. 2007; 9(12): 575-577  

Differential diagnosis and treatment of the edema of lower extremities

MUDr. Antonín Nechvátal

Interní Med. 2007; 9(12): 564-565  

Edema is defined as a clinically apparent increase in the interstitial fluid volume. Edema may be localized or generalized. Pathofyziological mechanisms are different. In the clinical practice are important differentiate chronic venous inufficiency, deep vein trombosis and lymfatic edema from other possible causes.

Delirium tremens

MUDr. Josef Chval

Interní Med. 2007; 9(12): 566-568  

In the article ended with two case reports, I summarized basic theoretical and practical findings of occurrence, diagnosis and treatment of alcohol withdrawal syndrome with delirium. I try to warn about the risks related to this disease and its treatment. In the article, I rely mostly on practical experiences with treatment of these patients in our department.

Boj s profesionální deformací

Mgr. Veronika Zachová, Dagmar Škochová

Interní Med. 2007; 9(12): 569-570