Změnila nutriční a metabolická péče tvář moderní intenzivní medicíny?

MUDr. Jan Maňák, Ph.D.

Interní Med. 2012; 14(1): 3  

Therapy of extraintestinal manifestations of inflammatory bowel disease

doc.MUDr.Zdena Zádorová, Ph.D.

Interní Med. 2012; 14(1): 8-11  

Inflammatory bowel disease (IBD) predominantly affects the gastrointestinal system but it is associated with a large number of extraintestinal manifestations (EIM). These extraintestinal disorders can significantly contribute to morbidity and impair the overall life quality. The most common extraintestinal disorders associated with IBD include dermatologic, ophthalmologic, musculoskeletal and hepatobiliary diseases, although virtually every organ system may be involved. It is important to acquire knowledge on these extraintestinal manifestations of Crohn‘s disease (CD) and ulcerative colitis (UC) to start the respective treatment early.

Use of bacterial lysates in clinical practice

doc.MUDr.Jaromír Bystroň, CSc.

Interní Med. 2012; 14(1): 12-17  

The author presents an overview of the past and present of the clinical use of bacterial lysates. The latest knowledge on the mechanisms of action of these agents is provided and also discussed are the indications and the most common issues concerning the use of bacterial lysates in clinical practice.

Autonomous neuropathy and affliction of the myocardium

MUDr.Alena Adamíková, Ph.D., MUDr.Jiří Bakala

Interní Med. 2012; 14(1): 18-20  

Cardiovascular autonomous neuropathy includes abnormalities in the control of cardiac frequency as well as in central and peripheral vascular dynamics. It afflicts ca 17 % of type 1 diabetic patients and 22 % of type 2 diabetic patients, depending on the method used for the examination. Diabetes mellitus leads to functional and structural changes of the myocardium, even independently of the presence of ischemic disease and hypertension. The finding of systolic and diastolic dysfunctions of the left ventricle, myocardial dilatations and hypertrophy without the presence of macroangiopathy is designated as diabetic cardiomyopathy. Among the causes...

Bursitis uratica

MUDr.Julius Vachtenheim, CSc.

Interní Med. 2012; 14(1): 21-22  

The purpose of this contribution is to refer about of a frequently incidence of bursitis, mainly localisated in elbow (olecranon) and knee (prepatellar) regions, as a gouty origin. It is very important just now, at time with a great incidence of gouty not-joint localisated signs. At time right diagnosed gouty bursitis, can the patients in a few hours and days be successfully restored.

Rizolli R, et al. Vliv stroncium ranelátu a alendronátu na mikrostrukturu kostí u žen s osteoporózou

MUDr. Petr Hrdý

Interní Med. 2012; 14(1): 40-42  

Hereditary angioedema and anaphylactic reaction after sting from hornets

MUDr.Jana Hanzlíková

Interní Med. 2012; 14(1): 34-37  

In patients with a long history of angioedema without urticaria was diagnosed hereditary angioedema (HAE) and launched a long-term prophylactic treatment with attenuated androgens danazol. The patient was at the time of diagnosis of HAE, unfortunately, also treated with ACE inhibitors for hypertension. After initiation of the therapy with danazol, and simultaneously change in therapy of hypertension with discontinuation of ACE inhibitors, the status of the patient improved markedly in recent years and symptoms of HAE appeared sporadically only during infection or following surgery. Since 2001 the patient after wasp or bee sting had a large...

Post-operative pain management

MUDr.Tomáš Gabrhelík, Ph.D., MUDr.Marek Pieran

Interní Med. 2012; 14(1): 23-25  

Every operation is connected with acute pain. Pain management is a common part of peri-operative care. Nowadays, we have got enough analgesics and techniques to accomplish this target. Balanced analgesia, specific procedure analgesia and a fine organisation of post-operative pain management are recommended methods in medical institutions. The aim of these procedures is appropriate post-operative pain management with low risk of side effects.

Prevention of cardioembolic stroke

doc.MUDr.Jiří Bauer, CSc.

Interní Med. 2012; 14(1): 26-29  

Anticoagulant therapy plays an important role in primary and secondary prevention of brain embolism in patients with non-valvular atrial fibrillation and other sources of cardioembolic strokes. The most commonly used anticoagulant in these indications is warfarin. Warfarin significantly reduces the risk of stroke and death, but increases that of bleeding. Life-threatening intracerebral haemorrhage is the most serious complication of anticoagulant therapy, with a mortality, that can exceed 50 %. New oral direct thrombin inhibitors (dabigatran) and factor Xa inhibitors (rivaroxaban, apixaban) present promising alternatives to warfarin. Dabigatran...

New trends in diagnostics and treatment of neuropathic pain

MUDr.Rudolf Černý, CSc.

Interní Med. 2012; 14(1): 30-32  

Author presents new classification and diagnostic algorithm for neuropathic pain. Next section gives overview of recent therapeutic guidelines – EFNS and IASP. Newly introduced drugs and local therapeutics are presented, along with the perspectives of future evolution of pharmacotherapy of the neuropathic pain. treatment.

Starvation in hospitals

MUDr.Zuzana Kala Grofová

Interní Med. 2012; 14(1): 38-39  

More than 20 millons of EU inhabitants suffer from undernutrition. 30–40 % patients admitted to hospitals are undernourished. Malnutrition is frequently their main reason for hospitalisation and in 2/3 of patients it gets worse during the hospital stay. Undernutrition is caused by starvation. The term starvation is often not understood correctly as insufficient food or nutrition intake. There are multiple reasons for hospital starvation including a professional blindness that leads to focusing on technologies and sophisticated methods more than on simple follow up the food intake and checking patients body weight. A complex treatment...